Antigen expression on recurrent meningioma cells

Antigen expression on recurrent meningioma cells

INTRODUCTION Meningiomas are intracranial brain tumours that frequently recur. Recurrence rates up to 20% in 20 years for benign meningiomas, up to 80% for atypical meningiomas and up to 100% for malignant meningiomas, have been reported. The most important prognostic factors for meningioma recurrence are meningioma grade, meningioma invasiveness and radicality of neurosurgical resection. The a...

Systemic Treatment of Recurrent Meningioma

Human Leukocyte Antigen-G Expression on Dendritic Cells Induced by Transforming Growth Factor-β1 and CD4+ T Cells Proliferation

Background: During antigen capture and processing, mature dendritic cells (DC) express large amounts of peptide-MHC complexes and accessory molecules on their surface. DC are antigen-presenting cells that have an important role in tolerance and autoimmunity. The transforming growth factor-beta1 (TGF-β1) cytokine has a regulatory role on the immune and non-immune cells. The aim of this study is ...

Recurrent atypical meningioma seeding to surgical scar.

thickened arachnoid. Cord was anteriorly adherent at D4 level. There was kinking and lateral rotation of the cord. Cord herniation through the small dural defect was identiÞ ed and reduction was done by microsurgery and the defect was closed with teß on graft. Patient had good recovery and was able to ambulate with support. Postoperative MRI revealed good reduction of the herniation and restora...

Acute recurrent haemorrhage of an intracranial meningioma.

Meningioma-associated haemorrhages are rare. To our knowledge this is the first report of a patient with an acute two-stage haemorrhage of a benign intracranial meningioma (World Health Organization grade I) verified by cranial CT scan and histopathological examination. Early surgery with complete tumour removal led to a good outcome for the patient.